Complete List of Publications
All Scientific Authors are listed in order of contribution with the exception of the corresponding author
* indicates corresponding/senior author
underlined authors indicate undergraduate students
94. De Novo Design, Synthesis, and Mechanistic Evaluation of Short Peptide That Mimic Heat Shock Protein 27 Activity Jessica Kho, P Chi Pham, Suhyeon Kwon, Alana Y Huang, Joel P Rivers, Huixin Wang, Heath Ecroyd, W Alexander Donald, Shelli R McAlpine*
ACS Med. Chem. Lett. V12, p713-719, 2021 doi.org/10.1021/acsmedchemlett.0c00609
93. Using NMR to identify binding regions for N and C-terminal Hsp90 inhibitors using Hsp90 domains. Jeanette R. McConnell, H. Jane Dyson*, Shelli R. McAlpine*. RSC Medicinal Chemistry V12, p410-415, 2021
92. Cyclic Peptides as drugs for intracellular targets: The next frontier in peptide therapeutic development Laura K. Buckton, Marwa N. Rahimi, and Shelli R. McAlpine * Chem. Eur. J. V27, V27, p1487-1513, 2021, DOI: 10.1002/chem.201905385
91. Real Time monitoring of peptide delivery in vitro using high payload pH responsive nanogels Shegufta Farazi, Fan Chen, Henry Foster, Raelene Boquiren, Shelli R. McAlpine, and Robert Chapman* Polym. Chem.V11, p425-432 2020, DOI: 10.1039/C9PY01120J
90. C-terminal Hsp90 inhibitors block the HIF-1 hypoxic response by degrading HIF-1a through the oxygen-dependent degradation pathway Nalin Kataria, Chloe-Anne Martinez, Bernadette Kerr, Samantha S. Zaiter, Monica Morgan, Shelli R. McAlpine and Kristina M Cook* Cell. Physiol. Biochem V53, p480-495 2019 DOI: 10.33594/000000152.
89. Polymer mediate transport of the Hsp90 inhibitor LB76, a polar resulting cyclic peptide, produces an Hsp90 cellular phenotype Marwa N. Rahimi, Henry G. Foster, Shegufta N. Farazi, Robert Chapman*, and Shelli R. McAlpine* Chem Commun, V55, p4515-4518 2019 DOI:10.1039/C9CC00890J
88. Delivering bioactive cyclic peptides that target Hsp90 as prodrugs Yuantao Huo, Laura K. Buckton, Jack L. Bennett, Eloise C. Smith, Frances, L. Byrne, Kyle L. Hoehn, Marwa N. Rahimi, and Shelli R. McAlpine* J. Enzyme Inhib. Med. Chem.V34, p728-739, 2019 DOI: 10.1080/14756366.2019.1580276
87. Protein-protein inhibitors designed de-novo to target the C-terminus of Hsp90 block co-chaperone activity Marwa N. Rahimi and Shelli R. McAlpine* Chem. Commun. V55, p846-849, 2019 DOI: 10.1039/C8CC07576J
86. Designing de novo small molecules that control Heat shock protein 70 within the chaperone machinery Samantha S. Zaiter, Yuantao Huo, Fong Ying Tiew, Jason E. Gestwicki, and Shelli R. McAlpine * J. Med. Chem. V62, p742-761, 2019 DOI:10.1021/acs.jmedchem.8b01436
85. Nanoparticles for bioapplications: Study of the cytotoxicity of water dispersible CdSe(S) and CdSe(S)/ZnO Quantum Dots F Mirnajafizadeh, D. Ramsey, S. R. McAlpine, F. Wang, P. Reece, J. Stride* Nanomaterials, V9 p465 2019 DOI: 10.3390/nano9030465
84. Functionalization of Quinazolin-4-Ones Part 3: Synthesis, structures, elucidation DNA-PK, PI3K and cytotoxicity of novel 8-aryl-2-morpholino-quinazolin-4-ones Jacob T. Heppella, MD. Amirul Islamc Shelli R McAlpine and Jasim M. A. Al-Rawi* J. Heterocycl. Chem., V56, p124-142 2019 DOI: 10.1002/jhet.3385 2019
83. Hsp90 mediates membrane deformation and exosome release Elsa Lauwers,* Yu-Chung Wang, Rodrigo Gallardo, Rob Van der Kant, Emiel Michiels, Jef Swerts, Pieter Baatsen, Samantha S. Zaiter, Shelli R. McAlpine, Natalia V. Gounko, Frederic Rousseau, Joost Schymkowitz, and Patrik Verstreken* Molecular Cell V71, p689-702, e9 2018 DOI: 10.1016/j.molcel.2018.07.016
82. Converting Polar cyclic peptides into cell permeable molecules using N-methylation Leo L. H. Lee, Laura K. Buckton* and Shelli R. McAlpine* Peptide Science, V110, e24063. 2018 DOI: 10.1002/pep2.24063
81. Improving the cell permeability of polar cyclic peptides by replacing residues with alkylated amino acids, asparagines, and D-amino acids Laura K. Buckton and Shelli R. McAlpine* Org. Lett. V20, p506-509, 2018
80. Synthesis and structure-activity relationships of inhibitors that target the C-terminal MEEVD on Heat shock protein 90 (Hsp90) Marwa N. Rahimi, Laura K. Buckton, Samantha S. Zaiter, Jessica Kho, Vickie Chan, Aldwin Guo, Jenane Konesan, SuHyeon Kwon, Lok K. O. Lam, Michael F. Lawler, Michael Leong, Gabriel D. Moldovan, David A. Neale, Gillian Thornton, and Shelli R. McAlpine* ACS Med. Chem. Lett. V9 p73-77 2018
79. RITA mimics: Synthesis and mechanistic evaluation of asymmetric linked Trithiazoles Adrian L. Pietkiewicz,† Yuqi Zhang,† Marwa N. Rahimi, Michael Stramandinoli, Matthew Teusner, and Shelli R. McAlpine* ACS Med. Chem. Lett. V8 p401-406 2017
78. Redefining the phenotype of Heat shock protein 90 (Hsp90) inhibitors Yao Wang, Yen Chin Koay, and Shelli R. McAlpine* Chem. Eur. J. V23 2010-2013 2017
77. How selective are Hsp90 inhibitors for cancer cells over normal cells? Yao Wang, Yen Chin Koay, and Shelli R. McAlpine* ChemMedChem V12 p353-357 2017
76. Allosteric Modulators of Heat Shock Protein 90 (HSP90) Yen Chin Koay and Shelli R. McAlpine * RSC Drug discovery series: “Allosterism in Drug Discovery” DOI: 10.1039/9781782629276, p404-426
75. Reinventing Hsp90 inhibitors: Blocking C-terminal binding events to Hsp90 using dimerized inhibitors Yen Chin Koay, Hendra Wahyudi Shelli R. McAlpine* Chem. Eur. J. V22, p18572-18582 2016
74. A novel class of Hsp90 C-terminal modulators have preclinical efficacy in prostate tumor cells without induction of a heat shock response Heather K. Armstrong, Yen Chin Koay, Swati Irani, Rajdeep Das, Zeyad D. Nassar, The Australian Prostate Cancer Bio resource, Luke A. Set, Margaret M. Centenera, Shelli R. McAlpine* and Lisa A. Butler* The Prostate V76, p1546-1559 2016
73. Hydrothermal synthesis of highly luminescent blue-emitting ZnSe(S) quantum dots exhibiting low toxicity Fatemeh Mimajafizadeh, Deborah Ramsey, Shelli R. McAlpine, Fan Wang, Peter Reece, and John Arron Stride*, Mat. Science and Eng. C V.64, p167-172 2016
72. Hitting a moving target: How does an N-Methyl group impact biological activity? Yen Chin Koay, Nicole L. Richardson, Samantha S. Zaiter, Jessica Kho, Sheena Y.Nguyen, Daniel H. Tran, Ka Wai Lee, Laura K. Buckton, , and Shelli R. McAlpine* ChemMedChem. V11, p881-892 2016
71. The first report of direct inhibitors that target the C-terminus MEEVD region on heat shock protein 90 Laura K. Buckton, Hendra Wahyudi, and Shelli R. McAlpine* Chem. Commun. V52, p501-504 2016
70. Hsp47: The new heat shock protein therapeutic target George Sharbeen, Shelli R. McAlpine, Phoebe Phillips* Springer Books: “Heat shock Proteins: Success Stories” 2016 DOI: 10.1007/7355_2015_89
69. Are some Hsp90 therapies more effective than others? Evaluating dual Hsp90 and Hsp70 inhibition as an anticancer therapy Laura K Buckton, Yao Wang, Jeanette R. McConnell, and Shelli R. McAlpine* Springer Books: “Heat shock Proteins: Success Stories” 2016 DOI: 10.1007/7355_2015_96.
68. Heat shock protein 27: structure, function, cellular Role and inhibitors Rashid Mehmood* and Shelli R. McAlpine* Springer Books: “Heat shock Proteins: Success Stories” 2016 DOI: 10.1007/7355_2015_94
67. Targeting the c-terminus of heat shock protein 90 as a cancer therapy Jeanette R McConnell, Yao Wang, Shelli R. McAlpine* Springer Books: “Heat shock Proteins: Success Stories” 2016 DOI: 10.1007/7355_2015_93
66. Synthesis of the natural product Marthiapeptide A Yuqi Zhang, Amirul Islam, and Shelli R. McAlpine* Org. Lett. V17, p5149-5151 2015
65. Blocking the heat shock response and depleting HSF-1 levels through heat shock protein 90 (hsp90) inhibition: A significant advance over current chemotherapies Yen Chin Koay, Jeanette R. McConnell, Yao Wang, and Shelli R. McAlpine* RSC Advances V5, 59003-59013 2015
64. Regulating the master regulator: controlling heat shock factor-1 as a chemotherapeutic Jeanette R. McConnell, Laura K Buckton, and Shelli R. McAlpine* Bioorg. Med. Chem Lett. V25, 3409-3414 2015
63. Thioimidazoline based compounds reverse glucocorticoid resistance in acute lymphoblastic leukemia cells Cara Toscan, Marwa Rahimi, Mohan Bhadbhade, Russell Pickford, Shelli R. McAlpine* and Richard Lock* Org. Biomol. Chem. V13, 6299-6312 2015
62. Predicting the unpredictable: recent examples of biologically active heterocycle-containing macrocycles Hendra Wahyudi and Shelli R. McAlpine* Bioorganic Chem. V60, 74-97 2015
61. Activation of the Nuclear Factor kB inducing kinase as a mechanism of beta cell failure in obesity Elisabeth K. Malle, Nathan W. Zammit, Stacey N. Walters, Yen Chin Koay, Jianmin, Wu, Bernice, M. Tan, Jeanette E. Villanueva, Robert Brink, Tom Loudovaris, James Cantley, Shelli R. McAlpine, Daniel Hesselson, Shane T. Grey* J. Exp. Med., V212, 1239-1254 2015
60. C-terminal heat shock protein 90 modulators produce desirable oncogenic properties Yao Wang and Shelli R. McAlpine* Org. Biomol. Chem, V13, 4627-4631 2015
59. Combining an Hsp70 inhibitor with either an N-terminal and C-terminal hsp90 inhibitor produces mechanistically distinct phenotypes Yao Wang and Shelli R. McAlpine* Org. Biomol. Chem. V13, 3691-3698 2015
58. Heat shock protein 90 inhibitors: will they ever succeed as chemotherapeutics? Yao Wang, and Shelli R. McAlpine* Future Med. Chem. V7, 2, 87-90 2015
57. Regulating the cytoprotective response in cancer cells using simultaneous inhibition of Hsp90 and Hsp70 Yao Wang, and Shelli R. McAlpine* Org. Biomol. Chem. V13, 2108-2116 2015
56. Design, Synthesis and anticancer activity of linked azoles Amirul Islam, Yuqi Zhang, Yao Wang, and Shelli R. McAlpine* Med. Chem. Comm. V6, 300-305 2015
55. The fungal natural product (1S, 3S)-austrocortirubin induces DNA damage via a mechanism unique from other DNA damaging agents Yao Wang∞,Md. Amirul Islam∞, Rohan A. Davis, and Shelli R. McAlpine* Bioorg. Med. Chem Lett. V25, 249-253 2015
54. N-terminal and C-terminal modulation of hsp90 produce dissimilar phenotypes Yao Wang and Shelli R. McAlpine* Chem. Comm. V51, 1410-1413 2015 COVER OF THE JOURNAL
53. HSP90 inhibitors and conjunctival melanoma M Madigan,* X. Quah, S. McAlpine, and R. M. Conway Acta Ophthalmologica. V92, s253 2014
52. Synthesis of macrocycles that inhibit protein synthesis: stereochemistry and structural based studies on sanguinamide B derivatives Adrian L Pietkiewicz, Hendra Wahyudi, Jeanette, R, McConnell, and Shelli R. McAlpine * Tetrahedron Lett. V55, 6979-6982 2014. COVER OF THE JOURNAL
51. Chemically accessible hsp90 inhibitor that does not induce a heat shock response Yen Chin Koay, Jeanette R. McConnell, Yao Wang, Seong Jong Kim, Laura K. Buckton, Flora Mansour and Shelli R. McAlpine* ACS Med. Chem. Lett. V5, 771-776, 2014
50. Synthesis and cytotoxicity of sanguinamide B analogs: identification of an active macrocyclic conformation Hendra Wahyudi, Worawan Tantisantisom, and Shelli R. McAlpine* Tetrahedron Lett. V55, 2389-2393, 2014 COVER OF THE JOURNAL
49. Recent Advances in Macrocyclic Hsp90 Inhibitors Deborah Ramsey, R.R. A Kitson, J. I Levin, C. J Moody*, and S. R. McAlpine* RSC Books: Macrocycles in Drug Discovery: DOI:10.1039/9781782623113-00037; p37-77 2014
48. A Heat shock protein 90 inhibitor that modulates the immunophilins and regulates hormone receptors without inducing a heat shock response Jeanette R. McConnell, Leslie D. Alexander, and Shelli R. McAlpine* Bioorg. Med. Chem Lett. V24, p661-666, 2014
47. Utilizing a Dimerization strategy to inhibit the dimer protein Hsp90: Synthesis and biological activity of a sansalvamide A dimer Hendra Wahyudi, Yao Wang, and Shelli R. McAlpine* Org. Biomol. Chem. V12, p765-773 2014
46. Total synthesis and biological activity of the natural product Urukthapelstatin A Chun Chieh Lin, Worawan Tantisantisom, and Shelli R. McAlpine* Org. Lett. V15, p3574-3577, 2013
45. Mechanism of action for a novel macrocycle: a small molecule inhibitor of the ribosome machinery Worawan Tantisantisom, Deborah M. Ramsey, and Shelli R. McAlpine* Org. Lett. V15, p4638-4641, 2013
44. Effectively delivering a drug using star polymers: Improving solubility of a unique hsp90 inhibitor Seong Jong Kim, Deborah M.
Ramsey, Cyrille Boyer, Thomas Davis, and Shelli R. McAlpine* ACS Med. Chem. Lett V4, p915-920, 2013
43. Novel Marine Natural Products that target the gram-positive Cell Wall Deborah M. Ramsey,* Amirul Islam, Rohan A. Davis, Cynthia B. Whitchurch, Lynne Turnbull and Shelli R. McAlpine* Bioorg. Med. Chem Lett. V23, p4862-4866, 2013
42. A potential Rhodium Cancer Therapy: studies of a cytotoxic organorhodium (I) complex that binds DNA Jeanette R. McConnell, Dimple P. Rananaware, Deborah M. Ramsey, Kai N. Buys, Marcus L. Cole and Shelli R. McAlpine* Bioorg. Med. Chem Lett. V23, p2527-2531 2013
41. Heat shock proteins 27, 40, and 70 as combinational therapeutic targets Jeanette R. McConnell and Shelli R. McAlpine* Bioorg. Med. Chem. Lett. V23, p1923-1928, 2013
40. An efficient synthetic route for synthesizing macrocycles that contain heterocycles: Solid Phase versus Solution Phase Synthesis Seong Jong Kim and Shelli R. McAlpine* Molecules V18, p1111-1121 2013
39. A structure-activity relationship study on multi-heterocyclic molecules: two linked thiazoles are required for cytotoxic activity Seong Jong Kim, Chun Chieh Lin, Chung-Mao Pan, Dimple P. Rananaware, Deborah M. Ramsey, and Shelli R. McAlpine* Med. Chem. Comm. V4 , p406-410, 2013
38. Halting Metastasis through CXCR4 inhibition Deborah M. Ramsey* and Shelli R. McAlpine* Bioorg. Med. Chem. Lett. V23, p20-25, 2013
37. Synthesis, structure-activity analysis, and biological evaluation of structurally related conformational isomers Hendra Wahyudi, Worawan Tantisantisom, Xuechao Liu, Deborah M. Ramsey, Erinprit K. Singh, and Shelli R. McAlpine* J. Org. Chem. v77, p10596-10616, 2012
36. A new Hsp90 inhibitor that exhibits a novel biological profile Deborah M. Ramsey, Jeanette R. McConnell, Leslie D. Alexander, Kaishin W. Tanaka, Chester M. Vera, and Shelli R. McAlpine* Bioorg. Med. Chem. Lett. v22, p3287-3290, 2012
35. Progress towards the synthesis of Urukthapelstatin A and two analogs Chung-Mao Pan, Chun-Chieh Lin, Seong Jong Kim, Robert P. Sellers, and Shelli R. McAlpine* Tetrahedron Lett., v53, p4065-4069, 2012
34. Total Synthesis of Natural Product trans,trans- Sanguinamide B and its structurally related conformational isomers Erinprit K. Singh, Deborah M. Ramsey, and Shelli R. McAlpine* Org. Lett. v14, p1198-1201, 2012
33. Synthesis of Sansalvamide A Peptidomimetics: Triazole Oxazole, Thiazole,and Pseudoproline containing compounds Melinda R. Davis, Erinprit K. Singh, Hendra Wahyudi, Leslie D. Alexander, Joseph Kunicki, Lidia A. Nazarova, Kelly A. Fairweather, Andrew Giltrap, Katrina A. Jolliffe, and Shelli R. McAlpine* Tetrahedron, v68, p1029-1051, 2012
32. Macrocycles that inhibit the binding between heat shock protein 90 and TPR-containing proteins Veronica C Ardi, Leslie D. Alexander, Victoria Johnson, and Shelli R. McAlpine* ACS Chem. Biol. v6, p1357-1367, 2011
31. Small Molecule Inhibitors of Hsp90’s Conformational Changes Leslie D. Alexander, James Partridge, David Agard, and Shelli R. McAlpine* Bioorg. Med. Chem. Lett. v21, p7068-7071, 2011
30. Synthesis and Evaluation of Biotinylated Sansalvamide A Analogs and their modulation of Hsp90 Joseph Kunicki, Mark Petersen, Leslie D. Alexander, Veronica C. Ardi, Jeanette R. McConnell, and Shelli R. McAlpine* Bioorg. Med. Chem. Lett, v21, p4716-4719, 2011
29. A third generation of Sansalvamide A derivatives: Design and synthesis of Hsp90 inhibitors Robert P. Sellers, Leslie D. Alexander, Victoria A. Johnson, Chun-Chieh Lin, Jeremiah Savage, Ricardo Corral, Jason Moss, Tim S. Slugocki, Erinprit K. Singh, Melinda R. Davis, Suchitra Ravula, Jamie E. Spicer, Jenna L Oelrich, Andrea Thornquist, Chung-Mao Pan, and Shelli R. McAlpine* Bioorg. Med. Chem. v18, p6822-6856 2010
28. Histone deactylace inhibitors: Synthesis of cyclic tetrapeptides & their triazole analogs Erinprit K. Singh, Lidia A. Nazarova, Stephanie A. Lapera, Leslie D. Alexander and Shelli R. McAlpine* Tetrahedron Lett. v51, p4357-4360 2010
27. Macrocyclic inhibitors of Hsp90 Victoria A. Johnson, Erinprit K. Singh, Lidia A. Nazarova, Leslie D. Alexander, and Shelli R. McAlpine* Curr. Top. Med. Chem. v23, p1380-1402 2010
26. Mechanistic studies of Sansalvamide A-amide:An allosteric modulator of Hsp90 Robert C. Vasko, Rodrigo A. Rodriguez, Christian Cunningham, Veronica Ardi, David Agard, and Shelli R. McAlpine* ACS Med. Chem. Lett. v1, p4-8 2010
25. Evaluation of Di-Sansalvamide A derivatives: synthesis, SAR, and Mechanism of action Leslie D. Alexander, Robert P. Sellers, Melinda R. Davis, Veronica C. Ardi, Victoria A. Johnson, Robert C. Vasko and Shelli R. McAlpine* J. Med. Chem. v52, p7927-7930 2009
24. A comprehensive study of Sansalvamide A derivatives: the structure-activity relationships of 78 derivatives in two pancreatic cancer cell lines Po-Shen Pan, Robert C. Vasko, Stephanie A. Lapera, Victoria A. Johnson, Robert P. Sellers, Chun-Chieh Lin, Chung-Mao Pan, Melinda R. Davis, Veronica C. Ardi and Shelli R. McAlpine* Bioorg. Med. Chem., v17, p5806-5825 2009
23. Structure-activity relationships of Sansalvamide A derivatives and their mechanism of action in the pancreatic cancer cell line PL-45 Rodrigo A. Rodriguez, Po-Shen Pan, Robert C. Vasko, Chung-mao Pan, William Disman, and Shelli R. McAlpine* J. Mex. Chem. Soc., v52, p201-211, 2008
22. Conformational based design of macrocycles as antitumor agents Erinprit K. Singh, Robert P. Sellers, Leslie D. Alexander and Shelli R. McAlpine* Curr. Opin. Drug Discovery Dev., v11, p544-552, 2008
21. Synthesis and biological evaluation of Histone Deacetylates inhibitors that are based on the FR235222 scaffold Erinprit Singh, Suchitra Ravula, Chung-mao Pan, Po-Shen Pan, Robert C. Vasko, Stephanie A. Lapera, Sujith, Mary Kay Pflum, and Shelli R. McAlpine* Bioorg. Med. Chem. Lett,v18, p2549-2554, 2008
20. Synthesis and cytotoxicity of a new class of potent decapeptide macrocycles Melinda R. Davis, Thomas J. Styers, Rodrigo A. Rodriguez, Po-Shen Pan, Robert C. Vasko, and Shelli R. McAlpine* Org. Lett., v10, p177-180, 2008
19. A comprehensive study of Sansalvamide A derivatives and their structure-activity relationships against drug-resistant colon cancer cell lines. Katerina Otrubova, Gerald H. Lushington, David Vander Velde, Kathleen L. McGuire, and Shelli R. McAlpine* J. Med. Chem., v51, p530-544, 2008
18. Identification of compounds potent against pancreatic cancer cell lines Po-Shen Pan, Kathleen L. McGuire, and Shelli R. McAlpine* Bioorg. Med. Chem. Lett., v17, p5072, 2007
17. A novel platform targeting drug-resistant colon cancers Katerina Otrubova, Kathleen L. McGuire and Shelli R. McAlpine* J. Med. Chem. v50, p1999- 2002, 2007
16. Synthesis of second generation Sansalvamide A derivatives: Novel Templates as Potential Anti-tumor Agents Rodrigo A. Rodriguez, Po-Shen Pan, Chung-Mao Pan, Suchitra Ravula, Stephanie Lapera, Erin Singh, Thomas J. Styers, Julia Cajica, Joseph D. Brown, Emily Parry, Katerina Otrubova, and Shelli R. McAlpine* J. Org. Chem., v72, p1980-2002, 2007
15. Synthesis of Sansalvamide A derivatives and their cytotoxicity in colon cancer cell line HT-29 Thomas J. Styers, Ahmet Kekec, Rodrigo Rodriguez, Joseph D. Brown, Julia Cajica, Chris L. Carroll, Po-Shen Pan, Irene Medina, Ricardo Corral, Jennifer V. C. Johnston, Emily Parry, Stephanie Lapera, Katerina Otrubova, Kathleen L. McGuire,* and Shelli R. McAlpine* Bioorg. Med. Chem., v14, p5625-5631, 2006
14. Novel Antibiotics: C-2 symmetrical macrocycles affecting Holliday Junction DNA processing Po-Shen Pan, Fiona A. Curtis, Chris L. Carroll, Irene Medina, Lisa A. Liotta, Gary J. Sharples, and Shelli R. McAlpine* Bioorg. Med. Chem., v14, p4731-4739, 2006
13. Synthesis and novel structure-activity relationships of potent Sansalvamide A derivatives Katerina Otrubova, Thomas J. Styers, Po-Shen Pan, Rodrigo Rodriguez, Kathleen L. McGuire,* and Shelli R. McAlpine* Chem. Commun. p1033-1034, 2006
12. Synthesis of novel Sansalvamide A Derivatives via new, high yielding macrocyclization conditions Thomas J. Styers, Rodrigo Rodriguez, Po-Shen Pan, and Shelli R. McAlpine* Tetrahedron Lett., v47, p515-517, 2006
11. Synthesis of novel anti-tumor agents: Sansalvamide A derivatives Chris L. Carroll, Jennifer V. C. Johnston, Ahmet Kekec, Joe Brown, Emily Parry, Julia Cajica, Irene Medina, Kristina M. Cook, Po-Shen Pan, and Shelli R. McAlpine* Org. Lett., v7 p3481-3484, 2005
10. Novel Antibiotics: second generation macrocyclic peptides designed to trap holliday junction Lisa A. Liotta, Irene Medina, Jennifer L. Robinson, Chris L. Carroll, Po-Shen Pan, Ricardo Corral, Jennifer V. C. Johnston, Kristina M. Cook, Fiona A. Curtis, Gary J. Sharples and Shelli R. McAlpine* Tetrahedron Lett., v45, p8447-8450 2004
9. Understanding Diseases via Receptor Regulation Shelli R. McAlpine Chem. and Biol., v11, p157-158 2004
8. A progressive synthetic strategy for Class B Synergimycins Jennifer L. Robinson, Rachel E. Taylor, Lisa A. Liotta, Megan L. Bolla Enrique V. Azevedo, Irene Medina, and Shelli R. McAlpine* Tetrahedron Lett., v45, p2147-2150 2004
7. Novel Antibiotics: Macrocyclic Peptides Designed to Trap Holliday Junctions MeganL. Bolla, Enrique V. Azevedo, Jason M.
Smith, Rachel E. Taylor, Dev K. Ranjit, Anca M. Segall, and Shelli R. McAlpine* Org. Lett., v5, p109-112 2003
6. Determination of Functional Group Distribution within Rasta Resins Utilizing Optical Analysis Shelli R. McAlpine*, Craig W.
Lindsley, John C. Hodges*, D. M. Leonard, G. F. Filzen J. Comb. Chem., v3, p.1-5 2001
Graduate and Post-doctoral publications
5. Visualizing Functional Group Distribution in Solid Support Beads using Optical Analysis Shelli R. McAlpine,* Stuart L. Schreiber, Chem.- Eur. J., v5, p.3528 1999
4. Studies of Naphthyl-Substituted –Cyclodextrins. Self-Aggregation and Inclusion of External Guests Shelli R. McAlpine,
Miguel A. Garcia-Garibay* J. Am. Chem. Soc., v120, p. 4269 1998
3. C32-O-Imidazol-2-yl-methyl Ether Derivatives of the Immunosuppressant Ascomycin with Improved Therapeutic Potential
M. T. Goulet*, S. R. McAlpine; M. Staruch;, S. Koprak, F. J. Dumont, J. G. Cryan, G. J. Wiederrecht, R. Rosa, M. B. Wilusz, L. B. Peterson,
M. J. Wyvratt, W. H. Parsons Bioorg. Med. Chem. Lett., v8, p.2253 1998
2. Binding Studies of Adamantanecarboxylic Acid and a Naphthyl-Bound -Cyclodextrinby Variable Temperature 1H NMR
S. R. McAlpine, M. A. Garcia-Garibay* J. Org. Chem., v61, p. 8307 1996
1. Inside-Outside Isomerism of -Cyclodextrin Covalently Linked with a Naphthyl Group S. R. McAlpine, M. A. Garcia-Garibay*
J. Am. Chem. Soc., v118, p. 2750-2751 1996
Other Publications
Life as an academic: being a female assistant professor in chemistry Shelli R. McAlpine American Chemical Society: Gladly We Teach, p57 2006